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5-Amino-1MQ
$49.99
5-Amino-1MQ is a small molecule compound (often referred to as a peptide in wellness contexts) that works by inhibiting the enzyme Nicotinamide N-methyltransferase (NNMT), which is involved in fat storage and metabolic slowdown. By blocking this enzyme, it boosts levels of the crucial coenzyme NAD+ and activates the longevity-associated sirtuin (SIRT1) genes, leading to several potential benefits primarily related to metabolic health.
Primary Potential Benefits
- Fat Loss and Weight Management: The main benefit is supporting fat metabolism and targeting stubborn fat, particularly visceral (abdominal) fat. It is being investigated for its potential to reverse and prevent diet-induced obesity in preclinical studies.
- Preservation of Lean Muscle Mass: Unlike some traditional weight loss methods that can lead to muscle loss, 5-Amino-1MQ helps maintain lean muscle mass while the body sheds fat.
- Increased Energy Levels: Users often report increased daily energy, endurance, and overall vitality, which is attributed to enhanced cellular energy production in the mitochondria.
- Improved Insulin Sensitivity: By reducing fat cell size and promoting balanced enzyme activity, it may help improve insulin sensitivity and blood sugar regulation, making it of interest for individuals with prediabetes, metabolic syndrome, or PCOS.
- Enhanced Metabolic Function: It boosts overall metabolism without the use of stimulants, allowing the body to burn calories more efficiently.
- Anti-Aging and Longevity Support: By increasing NAD+ levels and activating sirtuins (known as "longevity genes"), it may support healthy aging processes and cellular repair mechanisms.
Important Considerations
- Investigational Use: 5-Amino-1MQ is an experimental compound and is not approved by the FDA for the treatment of any disease in humans. Its use is considered off-label or investigational, and long-term safety data in humans is limited.
- Medical Supervision: It should only be used under the guidance of a licensed medical professional as part of a supervised program.
- Cycling of Use: The body may adapt to its effects over time, so it often needs to be cycled (e.g., used for 4-6 weeks followed by a 2-4 week break) to maintain effectiveness.
- Potential Side Effects: While generally considered well-tolerated, potential minor side effects can include gastrointestinal upset, headache, or difficulty sleeping if taken too late in the day.
- Contraindications: It is generally not recommended for individuals who are pregnant, breastfeeding, or have certain chronic conditions such as active cancer, unmanaged liver/kidney issues, or uncontrolled hypertension