Improves insulin sensitivity:MOTS-c appears to help cells, particularly in the skeletal muscles, use glucose more efficiently. In rodent studies, it reversed age- and diet-induced insulin resistance and improved glucose tolerance.
Aids in weight management:Research suggests MOTS-c can prevent diet-induced obesity in mice by increasing fat oxidation and improving the body's ability to burn fat for energy.
Boosts energy metabolism:By activating the AMPK pathway, MOTS-c promotes energy production and helps regulate overall cellular metabolism.
Exercise and muscle performance
Enhances physical performance:In aged mice, treatment with MOTS-c significantly improved running capacity and endurance, enabling them to outperform untreated middle-aged mice.
Supports muscle health:It appears to help protect muscle tissue from metabolic stress during exercise, which aids in recovery and repair.
Builds endurance:By enhancing the efficiency of mitochondria, MOTS-c can support greater stamina and exercise capacity.
Healthy aging and cellular resilience
Exhibits anti-aging effects:Since its levels naturally decline with age, MOTS-c is being studied for its potential to support healthy aging. It may combat age-related metabolic decline and delay the onset of physical impairments.
Promotes stress resistance:The peptide helps cells adapt to metabolic stress and protects against oxidative damage, a key factor in aging and disease.
Enhances longevity:Studies in mice have shown that late-life treatment with MOTS-c can increase healthy lifespan and improve physical capacity.
Other potential effects
Supports bone metabolism:Research indicates that MOTS-c may act as an anti-osteoporosis agent by suppressing osteoclast differentiation.
Provides immune system regulation:Studies show that MOTS-c may help regulate the immune system and has shown promise in preventing type 1 diabetes in mice.
Protects cardiovascular health:By activating the AMPK pathway, MOTS-c has shown protective effects against cardiac dysfunction and may help prevent heart failure.
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