While NAD+ is essential for many bodily functions and its levels decline with age, the benefits of NAD+ supplementation for human health and longevity are still under active investigation
. Much of the research has been conducted in animal models, showing promising results, but human clinical trials are less extensive.
Potential benefits from preclinical and early clinical research
Cellular energy and metabolism:NAD+ is a coenzyme critical for converting the energy from food into cellular energy (ATP). Supplementation is thought to help boost energy levels and metabolism.
Support for healthy aging:NAD+ levels naturally decline with age. Restoring NAD+ has been explored as a way to support healthy aging and reduce inflammation. Studies in animal models show it may increase lifespan.
Neurological health:NAD+ may improve cognitive function and reduce neuroinflammation, with some animal studies suggesting benefits for conditions like Alzheimer's disease.
Cardiovascular health:Research in preclinical models indicates that restoring NAD+ levels could improve heart function and reduce risk factors for cardiovascular disease.
DNA repair:NAD+ plays a vital role in DNA repair, a process that becomes less efficient with age. Boosting NAD+ may help repair DNA damage caused by oxidative stress.
Mental well-being:Some anecdotal reports and early studies suggest NAD+ supplementation may improve mood by influencing neurotransmitter balance and reducing symptoms of anxiety and depression. It has also been explored as a therapy for addiction recovery, particularly for reducing cravings and withdrawal symptoms.
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